This book features a selection of the best papers accepted for presentation and discussion at the 2025 International Conference in Information Systems and Medicine (ICISMED25). Held from 3 to 5 April 2025, ICISMED25 is a multidisciplinary conference with a particular focus on emerging technologies and systems in the healthcare sector. The event was supported by the Universidad Autónoma de Chile in Santiago and the International Association for Digital Transformation and Technological Innovation (IADITI). This book is intended for researchers, academics, lecturers, specialists, professionals, doctoral and master's students, undergraduates, and practitioners working at the intersection of healthcare and information technologies. The book addresses foundational and advanced concepts related to the paradigm of intelligent computing and communication within the context of distributed computing, big data, high-performance computing, and the Internet of Things (IoT), specifically applied to healthcare. Given the critical need to develop adaptive, intelligent, energy-efficient, secure, and privacy-aware mechanisms in high-performance and IoT-based healthcare applications, this book serves…

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