This book LNCS 15985 constitutes the proceedings of the 23rd International Workshop on Combinatorial Image Analysis, IWCIA 2025, held in Szeged, Hungary, during September 24–26, 2025. The 15 full papers were carefully reviewed and selected from 20 submissions. Image analysis provides the theoretical foundations and methodological tools essential for addressing complex real-world problems across diverse areas, including medicine, robotics, defense, and security.

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